ESR 8 : Calcium imaging of long-term memory traces in Anterior Cingulate Cortex

Supervisor: Dr. Clifford Kentros

M-GATE fellow: Lucie Descamps

To study later phases of the memory lifetime, electrophysiological methods are limited, because it is hard to obtain recordings of the same cells for a long period of time. For these purposes, calcium imaging has an advantage, because it enables long-term (weeks) recordings of large groups of cells. Here, we will search for the correlates of memory for objects in the anterior cingulate cortex, and their dependency on task requirements, to track precisely the stability of memory representations over long periods of time. Calcium signals and sequences analysis methods will be co-developed with ESR1 at INMED, INSCOPIX, and SISSA. Theoretical models from ESR10 will be applied.